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Nicotine Addiction in Britain

A report of the Tobacco Advisory Group of the Royal College of Physicians

Contributors, Foreword and Key Points

1  Tobacco smoking in Britain: an overview
1.1 History of tobacco use in Britain
1.2 Trends in smoking prevalence in Britain
1.3 Risk factors and determinants of cigarette smoking
1.4 Smoking in pregnancy
1.5 Morbidity and mortality caused by smoking
1.6 The costs of smoking in Britain
2 Physical and pharmacological effects of nicotine
2.1 Nicotine receptors and subtypes
2.2 Pharmacology and pharmacokinetics of nicotine
2.3 Pathophysiological effects and toxicity of nicotine
2.4 Effects of nicotine on mother and fetus in pregnancy
2.5 Animal self-administration and nicotine addiction
2.6 Nicotine neurochemistry: nicotine receptor and brain reward systems
3 Psychological effects of nicotine and smoking in man
3.1 The effects of nicotine and smoking on mood and cognition
3.2 The nicotine withdrawal syndrome
3.3 Psychological dependence on nicotine and smoking
4 Is nicotine a drug of addiction?
4.1 The definition of addiction and dependence
4.2 Does nicotine use through smoking meet standard diagnostic criteria for addiction?
4.3 The history of social, cultural and political responses to nicotine addiction in Britain
4.4 How does nicotine addiction compare with addiction to other drugs?
4.5 Relevance to society of recognition of nicotine as an addictive drug
5 The natural history of smoking: the smoker's career
5.1 Nicotine intake in novice smokers, and the development of dependence
5.2 Persistent and compulsive smoking in the face of smoking related ill-health
5.3 Non-dependent smokers
5.4 Smoking cessation rates in Britain
6 Regulation of nicotine intake for smokers, and implications for health
6.1 Titration and compensation
6.2 Epidemiological evidence on the effects of changes in tar and nicotine yields of cigarettes on disease risk
6.3 Does the epidemiological evidence support a direct relation between reduction in cigarette yields and disease risk?
7 The management of nicotine addiction
7.1 General and non-pharmacological approaches
7.2 Nicotine replacement therapy
7.3 Non-nicotine medications for treating nicotine addiction
7.4 Evidence-based treatment of nicotine addiction
7.5 Nicotine replacement treatment in pregnancy
7.6 Cost-effectiveness of treating nicotine addiction
8 Regulatory approaches to tobacco products in Britain
8.1 The evolution of British laws and voluntary agreements
8.2 The regulation of nicotine, tar and additives in cigarettes
8.3 Anomalies in current nicotine regulation
8.4 Novel nicotine delivery devices from tobacco companies
8.5 Tobacco regulation in the USA
8.6 Future nicotine regulation in the UK
8.7 Economic effects of nicotine regulation
9 Summary and recommendations
9.1 Tobacco and nicotine addiction
9.2 Consequences of nicotine addiction
9.3 Treatment of nicotine addiction
9.4 Regulation of tobacco products
9.5 Recommendations

 

 

This page last updated on May 4, 2001