Sepsis: recognition, diagnosis and early management - NICE guideline

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This guideline covers the recognition, diagnosis and early management of sepsis for all populations.

Sepsis: recognition, diagnosis and early management guideline committee identified that the key issues to be included were: recognition and early assessment, diagnostic and prognostic value of blood markers for sepsis, initial treatment, escalating care, identifying the source of infection, early monitoring, information and support for patients and carers, and training and education.

In July 2016, the accompanying algorithms and risk tables had some minor typographical errors corrected. Also, references to systolic blood pressure levels wrongly included in some algorithms for children were removed.


The guideline includes recommendations on:

Who is it for?

  • People with sepsis, their families and carers
  • Healthcare professionals working in primary, secondary and tertiary care

Related publications

  • Freitag A, Constanti M, O'Flynn N, Faust SN. Suspected sepsis: summary of NICE guidance. BMJ. 2016; 354:i4030
  • O'Fynn N. NICE Guideline: Sepsis. Critical Eye. 2017; 11(Winter 2017):10-11
  • Tavare A, O'Flynn N. Recognition, diagnosis, and early management of sepsis: NICE guideline. Br J Gen Pract. 2017; 67(657):185-186