The RCP holds the largest known collection of books from the library of John Dee (1527–1609). These were stolen from Dee in the 1580s by Nicholas Saunder, who left his own ownership marks on the books.
Renaissance polymath John Dee had many interests including cryptography, the art and science of making and breaking codes. Among the books once owned by Dee now in the RCP library is a copy of a cryptographic treatise by Johann Trithemius.