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Review of the evidence on interventions for prevention or treatment of dependence, short term discontinuation and longer term withdrawal symptoms associated with prescribed medicines.

This report gives a systematic review of the quantitative literature published in the last 10 years on the evidence of effectiveness of interventions for the prevention of or treatment for dependence, discontinuation or withdrawal related to the following medicines; benzodiazepines, Z drugs, GABA-ergic medication, opioid pain medications, antidepressants.